Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 2/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9440198 | 1.00 | HTT (0.44) | HTTKDM4ERARBRARARARG | |
| SCHEMBL9440220 | 0.83 | CPS1 (0.46) | — | |
| SCHEMBL9344940 | 0.80 | ALDH1A1 (0.57) | HTTKDM4ERARBRARARARG | |
| SCHEMBL7120872 | 0.80 | ALDH1A1 (0.57) | HTTKDM4ERARBRARARARG | |
| SCHEMBL8610288 | 0.80 | ALDH1A1 (0.57) | HTTKDM4ERARBRARARARG | |
| SCHEMBL7120866 | 0.80 | ALDH1A1 (0.57) | HTTKDM4ERARBRARARARG | |
| SCHEMBL9405633 | 0.78 | HTT (0.46) | HTTKDM4ERARBRARARARG | |
| SCHEMBL9405634 | 0.78 | HTT (0.46) | HTTKDM4ERARBRARARARG | |
| SCHEMBL9440304 | 0.78 | RARB (0.46) | RARBRARARARGALDH1A1 | |
| SCHEMBL7604332 | 0.78 | CA12 (0.40) | MEN1CYP3A4MAPTKMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341686-B1 | Novel halogen-containing ester compounds, and their intermediates, and method of producing the same as well as liquid crystal compositions containing the same and light switching elements | JAPAN ENERGY CORP (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-5098602-A | Aromatic ester derivatives and fluorophenol ketones | NIPPON MINING CO., LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| EP-0341686-A2 | Novel halogen-containing ester compounds, and their intermediates, and method of producing the same as well as liquid crystal compositions containing the same and light switching elements | JAPAN ENERGY CORPORATION (JP) | 1989-11-15 | — | — | EP | disclosed |