Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.44 |
| ▸ | BID | P55957 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9096019 | 0.86 | KCNH2 (0.66) | KCNH2BIDMCL1BCL2L1BAK1 | |
| SCHEMBL22096768 | 0.84 | KCNH2 (0.64) | KCNH2LTB4RBIDMCL1BCL2L1 | |
| SCHEMBL2274224 | 0.84 | KCNH2 (0.64) | KCNH2BIDMCL1BCL2L1BAK1 | |
| SCHEMBL5488837 | 0.84 | KCNH2 (0.62) | KCNH2BIDMCL1BCL2L1BAK1 | |
| SCHEMBL15440738 | 0.83 | KCNH2 (0.61) | KCNH2LTB4RBIDMCL1BCL2L1 | |
| SCHEMBL25137284 | 0.80 | KCNH2 (0.57) | KCNH2 | |
| Bicarbonate SCHEMBL10966197 | 0.80 | KCNH2 (0.78) | KCNH2LTB4RBIDMCL1BCL2L1 | |
| SCHEMBL6463178 | 0.79 | KCNH2 (1.00) | KCNH2GPR84 | |
| SCHEMBL10790586 | 0.79 | KCNH2 (1.00) | KCNH2GPR84 | |
| SCHEMBL31246249 | 0.79 | KCNH2 (1.00) | KCNH2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433457-B1 | ANTIPRURITIC COMPOSITION | SHISEIDO CO LTD (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5219847-A | Antipruritic composition | SHISEIDO COMPANY, LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0433457-A1 | ANTIPRURITIC COMPOSITION | SHISEIDO COMPANY LIMITED (JP) | 1991-06-26 | — | — | EP | disclosed |