Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM6B | O15054 | 1/20 | 0.52 |
| ▸ | TET3 | O43151 | 1/20 | 0.52 |
| ▸ | KDM4A | O75164 | 1/20 | 0.52 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.52 |
| ▸ | KDM5A | P29375 | 1/20 | 0.52 |
| ▸ | KDM5C | P41229 | 1/20 | 0.52 |
| ▸ | ASPH | Q12797 | 1/20 | 0.52 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.52 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.52 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.52 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.52 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.52 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.52 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.52 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9440315 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTKDM6BTET3 | |
| SCHEMBL2481383 | 0.98 | ALDH1A1 (0.53) | ALDH1A1KDM4EMAPTKDM6BTET3 | |
| SCHEMBL3092547 | 0.82 | TSHR (0.50) | ALDH1A1KDM4EMAPTSMN1; SMN2CYP3A4 | |
| Zinc Ion SCHEMBL9440309 | 0.82 | CA1 (0.44) | ALDH1A1KDM4EMAPTSMN1; SMN2TP53 | |
| SCHEMBL1850044 | 0.78 | GSK3B (0.51) | ALDH1A1KDM4EMAPTSMN1; SMN2PYGL | |
| SCHEMBL4037805 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTPYGLPYGM | |
| SCHEMBL3639473 | 0.78 | KDM4E (0.52) | ALDH1A1KDM4EMAPTTP53PYGL | |
| SCHEMBL29851386 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTSMN1; SMN2PYGL | |
| SCHEMBL18957459 | 0.77 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTSMN1; SMN2PYGL | |
| SCHEMBL31009101 | 0.77 | NPC1 (0.41) | ALDH1A1KDM4EMAPTSMN1; SMN2PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433457-B1 | ANTIPRURITIC COMPOSITION | SHISEIDO CO LTD (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5219847-A | Antipruritic composition | SHISEIDO COMPANY, LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0433457-A1 | ANTIPRURITIC COMPOSITION | SHISEIDO COMPANY LIMITED (JP) | 1991-06-26 | — | — | EP | disclosed |