Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1357035 | 0.84 | ALDH1A1 (0.50) | CYP3A4ALDH1A1CA2TDP1L3MBTL1 | |
| SCHEMBL1356320 | 0.84 | ALDH1A1 (0.50) | CYP3A4ALDH1A1CA2TDP1L3MBTL1 | |
| SCHEMBL762244 | 0.81 | CYP3A4 (0.45) | MAPTKMT2ACYP3A4ALDH1A1CA2 | |
| SCHEMBL10414307 | 0.80 | ALDH1A1 (0.44) | CYP3A4ALDH1A1CA2TDP1L3MBTL1 | |
| SCHEMBL9096619 | 0.79 | ALDH1A1 (0.49) | MAPTKMT2ACYP3A4ALDH1A1CA2 | |
| SCHEMBL20357876 | 0.79 | CYP3A4 (0.47) | CYP3A4ALDH1A1CA2TDP1L3MBTL1 | |
| SCHEMBL3335244 | 0.78 | MAPT (0.64) | MAPTKMT2ACYP3A4HSD17B10 | |
| SCHEMBL2272799 | 0.78 | ALDH1A1 (0.48) | MAPTKMT2ACYP3A4ALDH1A1CA2 | |
| SCHEMBL17053280 | 0.78 | ALDH1A1 (0.40) | CYP3A4ALDH1A1CA2TDP1L3MBTL1 | |
| SCHEMBL13053119 | 0.78 | ALDH1A1 (0.45) | CYP3A4ALDH1A1CA2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433457-B1 | ANTIPRURITIC COMPOSITION | SHISEIDO CO LTD (JP) | 1994-10-19 | — | — | EP | disclosed |
| US-5219847-A | Antipruritic composition | SHISEIDO COMPANY, LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0433457-A1 | ANTIPRURITIC COMPOSITION | SHISEIDO COMPANY LIMITED (JP) | 1991-06-26 | — | — | EP | disclosed |