Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 19/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9440485 | 0.81 | ALOX5 (0.44) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9035923 | 0.81 | ALOX5 (0.41) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9038451 | 0.80 | ALOX5 (0.43) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9440457 | 0.79 | ALOX5 (0.43) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9440584 | 0.78 | ALOX5 (0.48) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9050327 | 0.78 | ALOX5 (0.41) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9046867 | 0.77 | ALOX5 (0.39) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9048209 | 0.77 | ALOX5 (0.44) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9218816 | 0.77 | ALOX5 (0.44) | ALOX5PTGS1PTGS2 | |
| SCHEMBL9038104 | 0.76 | ALOX5 (0.51) | ALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225438-A | Lipoxygenase inhibitors for antiinflammatory agents or antiallergens | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | claimed |
| EP-0488602-A1 | Aryl derivatives | ZENECA LIMITED (GB) | 1992-06-03 | — | — | EP | claimed |
| US-5276037-A | Antiinflammatory agents, antiallergens | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-04 | — | — | US | disclosed |
| US-5272173-A | 5-lipoxygenase inhibitors | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-21 | — | — | US | disclosed |
| US-5225438-A | Lipoxygenase inhibitors for antiinflammatory agents or antiallergens | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| EP-0488602-A1 | Aryl derivatives | ZENECA LIMITED (GB) | 1992-06-03 | — | — | EP | disclosed |