SCHEMBL9440773

SCHEMBL9440773

CCc1c(Cl)cc(C(Oc2ccc(C(C)(C)CC)cc2C(C)(C)CC)C(N)=O)c(O)c1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 6/20 0.41
SMN1; SMN2 Q16637 5/20 0.41
NPSR1 Q6W5P4 5/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 4/20 0.33
HTT P42858 3/20 0.33
UBE2N P61088 2/20 0.33
GLA P06280 1/20 0.33
MITF O75030 1/20 0.33
ACACB O00763 1/20 0.33
RAB9A P51151 2/20 0.31
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31
CASP3 P42574 1/20 0.31
ATM Q13315 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3429177 0.77 KMT2A (0.39) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL8082860 0.75 KMT2A (0.38) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL7767207 0.74 MAPK1 (0.36) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL3293746 0.74 MAPK1 (0.53) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL8740989 0.74 MAPK1 (0.37) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL9336259 0.74 MAPK1 (0.44) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL8075464 0.73 SMN1; SMN2 (0.51) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL10634380 0.73 MAPK1 (0.54) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL7787748 0.73 NPSR1 (0.39) MAPK1SMN1; SMN2NPSR1MEN1KMT2A
SCHEMBL9353463 0.71 MAPK1 (0.52) MAPK1SMN1; SMN2NPSR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0244177-B1 Method for processing light-sensitive silver halide color photographic material KONISHIROKU PHOTO IND (JP) 1994-05-04 EP disclosed
US-4778743-A ALDEHYDE DERIVATIVE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-10-18 US disclosed
US-4778746-A COLOR DEVELOPING, FIXING, STABILIZATION WITHOUT WASHING KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-10-18 US disclosed
US-4774169-A AMINOPHOSPHONIC ACIDS AND AMINOCARBOXYLIC ACIDS IN DEVELOPER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-09-27 US disclosed
EP-0244177-A2 Method for processing light-sensitive silver halide color photographic material KONICA CORPORATION (JP) 1987-11-04 EP disclosed
US-4623616-A DIFFUSIONPROOF COUPLER, TRIAZINE HARDENING AGENT KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-11-18 US disclosed