Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | PPOX | P50336 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | GALR2 | O43603 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9442003 | 0.81 | SMN1; SMN2 (0.42) | TDP1SMN1; SMN2KMT2AMEN1TTR | |
| SCHEMBL9555718 | 0.81 | SMN1; SMN2 (0.42) | TDP1SMN1; SMN2KMT2AMEN1TTR | |
| SCHEMBL29034725 | 0.81 | TDP1 (0.58) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL16394208 | 0.81 | TDP1 (0.53) | TDP1SMN1; SMN2KMT2AMEN1TTR | |
| SCHEMBL9552008 | 0.80 | TDP1 (0.44) | TDP1SMN1; SMN2KMT2AMEN1TTR | |
| Lactofen SCHEMBL29462400 | 0.80 | MEN1 (0.66) | TDP1SMN1; SMN2KMT2AMEN1TTR | |
| Lactofen SCHEMBL30606811 | 0.80 | MEN1 (0.66) | TDP1SMN1; SMN2KMT2AMEN1TTR | |
| Lactofen SCHEMBL30359837 | 0.80 | MEN1 (0.66) | TDP1SMN1; SMN2KMT2AMEN1TTR | |
| Lactofen SCHEMBL8536001 | 0.80 | MEN1 (0.66) | TDP1SMN1; SMN2KMT2AMEN1TTR | |
| Lactofen SCHEMBL9796531 | 0.80 | MEN1 (0.66) | TDP1SMN1; SMN2KMT2AMEN1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266552-A | Biological antigrowth agents for plants | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-11-30 | — | — | US | disclosed |
| US-5234895-A | Arylpyridone herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-08-10 | — | — | US | disclosed |
| US-5232895-A | Postemergence herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-08-03 | — | — | US | disclosed |
| US-5205852-A | Postemergence herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-04-27 | — | — | US | disclosed |
| US-5186733-A | Arylphosphonodiamide compounds and herbicidal compositions thereof | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-16 | — | — | US | disclosed |
| US-5182402-A | 2-Phenylthiazolecarboxylic Acids and Esters | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-01-26 | — | — | US | disclosed |
| US-5120869-A | HERBICIDAL COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-06-09 | — | — | US | disclosed |