Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | PPOX | P50336 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 3/20 | 0.31 |
| ▸ | PPARD | Q03181 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29034725 | 0.82 | TDP1 (0.58) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL9552009 | 0.81 | TDP1 (0.41) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL9442005 | 0.80 | TDP1 (0.45) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL7148282 | 0.80 | MEN1 (0.69) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL28366683 | 0.76 | SCN9A (0.46) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL11671714 | 0.68 | TDP1 (0.78) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL10786523 | 0.67 | TDP1 (0.62) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL10685122 | 0.67 | TDP1 (0.74) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL11057422 | 0.66 | TDP1 (0.70) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL9575568 | 0.66 | MEN1 (0.67) | TDP1KMT2AMEN1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189169-A | Postemergence herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-23 | — | — | US | disclosed |
| US-5084083-A | Phenylthiazolecarboxylic acid derivative herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-28 | — | — | US | disclosed |