Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172785 | 1.00 | TDP1 (0.60) | TDP1SIGMAR1EPHX2DPP4NR1H2 | |
| SCHEMBL2895324 | 0.86 | TDP1 (0.64) | TDP1SIGMAR1EPHX2DPP4NR1H2 | |
| SCHEMBL2895326 | 0.86 | TDP1 (0.64) | TDP1SIGMAR1EPHX2DPP4NR1H2 | |
| SCHEMBL2895322 | 0.86 | TDP1 (0.64) | TDP1SIGMAR1EPHX2DPP4NR1H2 | |
| SCHEMBL23170436 | 0.84 | TDP1 (0.58) | TDP1SIGMAR1EPHX2DPP4NR1H2 | |
| SCHEMBL13028980 | 0.83 | TDP1 (0.57) | TDP1SIGMAR1EPHX2DPP4NR1H2 | |
| SCHEMBL24105937 | 0.81 | TDP1 (0.56) | TDP1SIGMAR1EPHX2DPP4NR1H2 | |
| SCHEMBL172970 | 0.81 | SIGMAR1 (0.61) | TDP1SIGMAR1EPHX2DPP4NR1H2 | |
| SCHEMBL16301132 | 0.80 | TDP1 (0.55) | TDP1SIGMAR1EPHX2DPP4NR1H2 | |
| SCHEMBL4872520 | 0.80 | SIGMAR1 (0.60) | TDP1SIGMAR1EPHX2DPP4NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000945-A9 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-04-07 | — | — | WO | disclosed |
| WO-2011000945-A2 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-01-06 | — | — | WO | disclosed |