Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARD | Q03181 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL28123564 | 0.74 | LMNA (0.65) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL31344500 | 0.72 | LMNA (0.43) | TSHRLMNANFKB1PMP22MEN1 | |
| SCHEMBL8091272 | 0.71 | LMNA (0.65) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL2371273 | 0.71 | LMNA (0.65) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL25186232 | 0.71 | TSHR (1.00) | TSHRLMNANFKB1PMP22GPR84 | |
| Sebacic Acid SCHEMBL301600 | 0.71 | TSHR (1.00) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL166746 | 0.71 | TSHR (1.00) | TSHRLMNANFKB1PMP22GPR84 | |
| Sebacic Acid SCHEMBL20500595 | 0.71 | TSHR (1.00) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL21065467 | 0.71 | TSHR (1.00) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL1674812 | 0.71 | TSHR (1.00) | TSHRLMNANFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258507-A | FOR IN SITU DETECTION OF NUCLEIC ACID SEQUENCES | AMOCO CORPORATION (US) | 1993-11-02 | — | — | US | disclosed |
| EP-0485155-A1 | Novel labeling reagents useful for the chemical attachment of nitrophenyl derivative ligands to DNA probes | AMOCO CORPORATION (US) | 1992-05-13 | — | — | EP | disclosed |