Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | CA7 | P43166 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11213860 | 0.91 | CA1 (0.57) | CA1CA2CA12CA7CA9 | |
| SCHEMBL6575703 | 0.86 | CA1 (0.61) | CA1CA2CA12CA7CA9 | |
| SCHEMBL9315234 | 0.86 | RAB9A (0.69) | TSHRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28993944 | 0.85 | CA1 (0.80) | CA1CA2CA12CA7CA9 | |
| SCHEMBL23600 | 0.85 | CA1 (0.80) | CA1CA2CA12CA7CA9 | |
| SCHEMBL749776 | 0.84 | MAPT (0.66) | CA1CA2CA12CA7CA9 | |
| Ammonia Solution, Strong SCHEMBL28873355 | 0.83 | CA1 (0.76) | CA1CA2CA12CA7CA9 | |
| Water SCHEMBL22720573 | 0.83 | CA1 (0.76) | CA1CA2CA12CA7CA9 | |
| Methyl Alcohol SCHEMBL28561085 | 0.83 | CA1 (0.76) | CA1CA2CA12CA7CA9 | |
| SCHEMBL28704033 | 0.83 | CA1 (0.76) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342724-A | Preparing polyester from diol and diacid wherein one of the monomers has disulfuide linkage, reacting polyester with unsaturated monomer to create addition polymer blocks linked by sulfide group from dislufide linkage | EASTMAN KODAK COMPANY (US) | 1994-08-30 | — | — | US | claimed |
| EP-3292893-B1 | GOLF BALL | SUMITOMO RUBBER IND (JP) | 2021-06-09 | — | — | EP | disclosed |
| EP-2656882-B1 | Golf ball | SUMITOMO RUBBER IND (JP) | 2021-06-09 | — | — | EP | disclosed |
| EP-3468956-B1 | 6-HYDROXY-5-(PHENYL/HETEROARYLSULFONYL)PYRIMIDIN-4(1H)-ONES AS APJ AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-03-03 | — | — | EP | disclosed |
| EP-3468956-B1 | 6-HYDROXY-5-(PHENYL/HETEROARYLSULFONYL)PYRIMIDIN-4(1H)-ONES AS APJ AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-03-03 | — | — | EP | disclosed |
| EP-3156441-B1 | GOLF BALL | SUMITOMO RUBBER IND (JP) | 2020-11-25 | — | — | EP | disclosed |
| EP-3329971-B1 | GOLF BALL | SUMITOMO RUBBER IND (JP) | 2020-11-18 | — | — | EP | disclosed |
| EP-2666521-B1 | Golf ball | SUMITOMO RUBBER IND (JP) | 2020-09-02 | — | — | EP | disclosed |
| US-20190194173-A1 | 6-HYDROXY-5-(PHENYL/HETEROARYLSULFONYL)PYRIMIDIN-4(1H)-ONE AS APJ AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2019-06-27 | — | — | US | disclosed |
| US-20190194173-A1 | 6-HYDROXY-5-(PHENYL/HETEROARYLSULFONYL)PYRIMIDIN-4(1H)-ONE AS APJ AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2019-06-27 | — | — | US | disclosed |
| EP-0494621-A1 | Substituted alkenoic acid and its derivatives | BAYER AG (DE) | 1992-07-15 | — | — | EP | disclosed |
| US-5002960-A | Viricides for combating picornaviruses | STERLING DRUG, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0410241-A1 | Aryl alkenoic acid derivatives as leukotriene antagonists | BAYER AG (DE) | 1991-01-30 | — | — | EP | disclosed |
| US-4939267-A | Viricides | STERLING DRUG INC. (US) | 1990-07-03 | — | — | US | disclosed |
| EP-0206662-B1 | THIAZOLIDINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | Tanabe Seiyaku Co., Ltd. (JP) | 1990-05-09 | — | — | EP | disclosed |
| US-4843087-A | OXAZOLINYL COMPOUNDS; RHINOVIRUSES AND PICORNAVIRUSES | STERLING DRUG INC. (US) | 1989-06-27 | — | — | US | disclosed |
| US-4777178-A | CARDIOTONIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1988-10-11 | — | — | US | disclosed |
| US-4689327-A | N-substituted-2-[2-[2-(4-phenylpiperazine-1-yl)ethoxy]phenyl]-thiazolidine-3-carboxamides useful as cardiotonic agent | TANABE SEIYAKU CO., LTD. (JP) | 1987-08-25 | — | — | US | disclosed |
| EP-0206662-A1 | Thiazolidine derivatives and process for preparing the same | Tanabe Seiyaku Co., Ltd. (JP) | 1986-12-30 | — | — | EP | disclosed |
| EP-0167355-A2 | Thiazolidine derivative and processes for preparing the same | Tanabe Seiyaku Co., Ltd. (JP) | 1986-01-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194173-A1 | 6-HYDROXY-5-(PHENYL/HETEROARYLSULFONYL)PYRIMIDIN-4(1H)-ONE AS APJ AGONISTS | TBXA2R, GPBAR1, CYP2J2 | CA1 4749/4885CA2 3131/4885CA12 4864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.