Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28398483 | 0.87 | MAPT (0.64) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL30023422 | 0.85 | MAPT (0.66) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL2446110 | 0.85 | MAPT (0.66) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL28401771 | 0.84 | MAPT (0.64) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL15628245 | 0.83 | MAPT (0.48) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL15621175 | 0.83 | MAPT (0.59) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL6444260 | 0.83 | MAPT (0.77) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL7947089 | 0.83 | MAPT (0.62) | MAPTKDM4EHSD17B10MAPK1ALOX15 | |
| SCHEMBL700669 | 0.82 | MAPT (0.66) | MAPTKDM4EMAPK1LMNAHTT | |
| SCHEMBL27978300 | 0.81 | MAPT (0.60) | MAPTKDM4EHSD17B10MAPK1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223513-A | Anticholesterol agent | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-06-29 | — | — | US | disclosed |