SCHEMBL6444260

SCHEMBL6444260

COc1ccc(C(=O)c2ccccc2)c(O)c1OC

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.77
KDM4E B2RXH2 5/20 0.77
HSD17B10 Q99714 3/20 0.77
MAPK1 P28482 3/20 0.77
ALOX15 P16050 2/20 0.77
TDP1 Q9NUW8 2/20 0.68
LMNA P02545 6/20 0.61
HTT P42858 2/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
NPSR1 Q6W5P4 1/20 0.61
HPGD P15428 6/20 0.58
ALDH1A1 P00352 3/20 0.58
CYP3A4 P08684 2/20 0.58
RECQL P46063 2/20 0.58
CYP1A2 P05177 2/20 0.53
CYP2D6 P10635 2/20 0.53
CYP2C19 P33261 2/20 0.53
PGR P06401 1/20 0.53
SLC6A2 P23975 1/20 0.53
PDE4A P27815 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9339159 0.87 MAPT (0.77) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL29260274 0.87 MAPT (0.67) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL2446110 0.87 MAPT (0.66) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL93271 0.87 MAPT (1.00) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL30023422 0.87 MAPT (0.66) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL27713896 0.86 MAPT (0.76) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL28401771 0.85 MAPT (0.64) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL25381912 0.85 MAPT (0.64) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL7947089 0.84 MAPT (0.62) MAPTKDM4EHSD17B10MAPK1ALOX15
SCHEMBL7333834 0.84 MAPT (0.63) MAPTKDM4EHSD17B10MAPK1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114316846-A Glue film composition containing polystyrene microspheres and preparation method and application thereof 苏州赛伍应用技术股份有限公司 2022-04-12 CN claimed
CN-114149769-A High-reflection black adhesive film and preparation method and application thereof 苏州赛伍应用技术股份有限公司 2022-03-08 CN claimed
EP-0360353-A2 Plate of material with polymeric structure, resistant to sun light LA/ES LAMINATI ESTRUSI TERMOPLASTICI S.P.A. (IT) 1990-03-28 EP claimed
CN-114316846-A Glue film composition containing polystyrene microspheres and preparation method and application thereof 苏州赛伍应用技术股份有限公司 2022-04-12 CN disclosed
CN-114149769-A High-reflection black adhesive film and preparation method and application thereof 苏州赛伍应用技术股份有限公司 2022-03-08 CN disclosed
US-20150218336-A1 UV ABSORBERS ON PIGMENTS EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2015-08-06 US disclosed
WO-2014028007-A1 UV ABSORBERS ON PIGMENTS EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-02-20 WO disclosed
US-20080269191-A1 Compounds for Nonsense Suppression, Use of These Compounds for the Manufacture of a Medicament for Treating Somatic Mutation-Related Diseases PTC THERAPEUTICS, INC. (US) 2008-10-30 US disclosed
US-20080269191-A1 Compounds for Nonsense Suppression, Use of These Compounds for the Manufacture of a Medicament for Treating Somatic Mutation-Related Diseases PTC THERAPEUTICS, INC. (US) 2008-10-30 US disclosed
CN-1714121-A Use of polymer powder containing UV absorber for the stabilisation of polymers against the effects of UV radiation BASF AG (DE) 2005-12-28 CN disclosed
EP-1565522-A2 USE OF POLYMER POWDER CONTAINING UV ABSORBER FOR THE STABILISATION OF POLYMERS AGAINST THE EFFECTS OF UV RADIATION BASF AKTIENGESELLSCHAFT (DE) 2005-08-24 EP disclosed
EP-1392283-A4 SUBSTITUTED COUMARINS AND QUINOLINES AS CASPASE ACTIVATORS CYTOVIA INC (US) 2004-10-20 EP disclosed
WO-2004046234-A2 USE OF POLYMER POWDER CONTAINING UV ABSORBER FOR THE STABILISATION OF POLYMERS AGAINST THE EFFECTS OF UV RADIATION BASF AKTIENGESELLSCHAFT (DE) 2004-06-03 WO disclosed
EP-1392283-A1 SUBSTITUTED COUMARINS AND QUINOLINES AS CASPASES ACTIVATORS Cytovia, Inc. (US) 2004-03-03 EP disclosed
WO-2002092076-A1 SUBSTITUTED COUMARINS AND QUINOLINES AS CASPASES ACTIVATORS CYTOVIA, INC. (US) 2002-11-21 WO disclosed
EP-0442068-B1 Benzophenone derivatives and polymers containing phenolic hydroxyl groups BAYER AG (DE) 1994-06-08 EP disclosed
EP-0442068-A2 Benzophenone derivatives and polymers containing phenolic hydroxyl groups BAYER AG (DE) 1991-08-21 EP disclosed
EP-0360353-A2 Plate of material with polymeric structure, resistant to sun light LA/ES LAMINATI ESTRUSI TERMOPLASTICI S.P.A. (IT) 1990-03-28 EP disclosed
US-4022908-A Use of certain 2-nitro-3-phenyl-alkoxybenzofurans in inhibiting growth of microorganisms and intermediates in the synthesis of said benzofurans RIKER LABORATORIES, INC. (US) 1977-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269191-A1 Compounds for Nonsense Suppression, Use of These Compounds for the Manufacture of a Medicament for Treating Somatic Mutation-Related Diseases UPF1, NSUN2, RNMT MAPT 2955/4885KDM4E 1079/4885HSD17B10 3455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.