Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 3/20 | 1.00 |
| ▸ | PRKCG | P05129 | 3/20 | 1.00 |
| ▸ | PRKCB | P05771 | 3/20 | 1.00 |
| ▸ | PRKCA | P17252 | 3/20 | 1.00 |
| ▸ | PRKCH | P24723 | 3/20 | 1.00 |
| ▸ | PRKCI | P41743 | 3/20 | 1.00 |
| ▸ | PRKCE | Q02156 | 3/20 | 1.00 |
| ▸ | PRKCQ | Q04759 | 3/20 | 1.00 |
| ▸ | PRKCZ | Q05513 | 3/20 | 1.00 |
| ▸ | PRKCD | Q05655 | 3/20 | 1.00 |
| ▸ | PRKD1 | Q15139 | 3/20 | 1.00 |
| ▸ | VEGFA | P15692 | 2/20 | 0.89 |
| ▸ | PGF | P49763 | 2/20 | 0.89 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.89 |
| ▸ | FLT1 | P17948 | 1/20 | 0.81 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.76 |
| ▸ | MMP2 | P08253 | 4/20 | 0.75 |
| ▸ | MMP9 | P14780 | 4/20 | 0.75 |
| ▸ | SNCA | P37840 | 3/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cinnamtannin B1 SCHEMBL13284073 | 1.00 | PRKD3 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Cinnamtannin B1 SCHEMBL29564472 | 1.00 | PRKD3 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL16063172 | 1.00 | PRKD3 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Cinnamtannin B1 SCHEMBL14595057 | 1.00 | PRKD3 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Cinnamtannin B1 SCHEMBL20801024 | 1.00 | PRKD3 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Cinnamtannin D1 SCHEMBL20789227 | 1.00 | PRKD3 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Cinnamtannin B1 SCHEMBL20814412 | 1.00 | PRKD3 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Cinnamtannin B1 SCHEMBL20814634 | 1.00 | PRKD3 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Cinnamtannin B1 SCHEMBL20801029 | 1.00 | PRKD3 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Cinnamtannin B1 SCHEMBL29376280 | 1.00 | PRKD3 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8415489-B2 | Synthesis of polycyclic procyanidins | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2013-04-09 | — | — | US | disclosed |
| US-8138358-B2 | Synthesis of polycyclic procyanidins | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2012-03-20 | — | — | US | disclosed |
| US-20120059175-A1 | SYNTHESIS OF POLYCYCLIC PROCYANIDINS | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-7615649-B2 | cyclization; prepare bioactive polyphenols in lab, which has similar structure as derived from cinnamon; antimicrobial, antiviral and antiprotozoal activity | Iowa State University Research Foundation, Inc, (US) | 2009-11-10 | — | — | US | disclosed |
| US-20070173543-A1 | SYNTHESIS OF POLYCYCLIC PROCYANIDINS | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2007-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173543-A1 | SYNTHESIS OF POLYCYCLIC PROCYANIDINS | PROC, ADH1C, UGT1A7 | PRKD3 3558/4885PRKCG 1427/4885PRKCB 1204/4885 |
| US-20120059175-A1 | SYNTHESIS OF POLYCYCLIC PROCYANIDINS | ADH1C, PROC, CCNC | PRKD3 3870/4885PRKCG 1525/4885PRKCB 1453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.