Thiourea

Thiourea

SCHEMBL9443298

CCCC(C)C.CCCC(C)C.NC(N)=S.NC(N)=S

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.39
CA1 P00915 5/20 0.36
CA2 P00918 4/20 0.36
CA12 O43570 3/20 0.36
CA9 Q16790 3/20 0.36
ATM Q13315 1/20 0.35
ATR Q13535 1/20 0.35
METAP1 P53582 2/20 0.34
OPRM1 P35372 1/20 0.32
CHRM1 P11229 1/20 0.32
AKR1A1 P14550 1/20 0.32
CHRM3 P20309 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32
HRH1 P35367 1/20 0.32
DRD3 P35462 1/20 0.32
SLC6A3 Q01959 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pentane SCHEMBL10425869 0.92 OPRM1 (0.39) TSHRCA1CA2CA12CA9
Hydrogen Peroxide SCHEMBL18614730 0.81
SCHEMBL4635 0.80
SCHEMBL29399686 0.80
SCHEMBL2487739 0.80
SCHEMBL907968 0.80 TSHR (0.44) TSHRCA1METAP1OPRM1CHRM1
SCHEMBL28418575 0.80 TSHR (0.38) TSHRCA1CA2METAP1OPRM1
Propionamide SCHEMBL14344179 0.78 CHRM1 (0.40) TSHRCA1CA2METAP1CHRM1
Isopropyl Alcohol SCHEMBL2245070 0.78 TSHR (0.45) TSHRCA1METAP1CHRM1AKR1A1
Hypochlorous Acid SCHEMBL11410814 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0423251-A4 ASSAY FOR QUALITATIVE AND QUANTITATIVE DETECTION OF ORGANIC AND INORGANIC ANALYTES OF DIVERSE CHEMICAL CLASSES VIA THE SELECTIVE FORMATION AND GROWTH OF LIGHT SCATTERING CRYSTALS 1993-06-09 EP disclosed