Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | DGKA | P23743 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10426125 | 0.93 | TSHR (0.68) | TSHRHPGDALDH1A1CYP3A4NAAA | |
| SCHEMBL1673486 | 0.93 | TSHR (0.79) | TSHRHPGDALDH1A1CYP3A4NAAA | |
| SCHEMBL10030735 | 0.92 | DGKA (0.68) | TSHRHPGDALDH1A1CYP3A4NAAA | |
| SCHEMBL9417606 | 0.91 | TSHR (0.76) | TSHRHPGDALDH1A1CYP3A4NAAA | |
| SCHEMBL13779732 | 0.90 | TSHR (0.73) | TSHRHPGDALDH1A1CYP3A4NAAA | |
| SCHEMBL16327390 | 0.90 | TSHR (0.68) | TSHRHPGDALDH1A1CYP3A4NAAA | |
| SCHEMBL2610341 | 0.90 | TSHR (0.72) | TSHRHPGDALDH1A1CYP3A4NAAA | |
| SCHEMBL2467554 | 0.89 | TSHR (0.72) | TSHRHPGDALDH1A1CYP3A4NAAA | |
| SCHEMBL7647533 | 0.89 | TSHR (0.84) | TSHRHPGDALDH1A1CYP3A4NAAA | |
| SCHEMBL21218910 | 0.89 | TSHR (0.84) | TSHRHPGDALDH1A1CYP3A4NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243069-A | Radiation curable, coatings, adhesives, binders | ROHM AND HAAS COMPANY (US) | 1993-09-07 | — | — | US | disclosed |
| US-4588788-A | CARBOXYETHYL ACRYLATE ESTERS | ROHM AND HAAS COMPANY (US) | 1986-05-13 | — | — | US | disclosed |