Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | PPOX | P50336 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | EIF4E | P06730 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | HPD | P32754 | 3/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27481992 | 0.87 | TDP1 (0.64) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL28323202 | 0.83 | TDP1 (0.51) | TDP1MEN1TTRPPOXKMT2A | |
| Water SCHEMBL11042053 | 0.83 | TDP1 (0.51) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL9555504 | 0.81 | TDP1 (0.77) | TDP1MEN1TTRPPOXKMT2A | |
| Ether SCHEMBL11042007 | 0.77 | MEN1 (0.48) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL9783673 | 0.74 | KMT2A (0.43) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL9442020 | 0.74 | MEN1 (0.42) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL11061094 | 0.73 | CHEK1 (0.48) | TDP1MEN1TTRPPOXKMT2A | |
| Water SCHEMBL9575739 | 0.73 | MEN1 (0.44) | TDP1MEN1TTRPPOXKMT2A | |
| Ether SCHEMBL11350608 | 0.73 | MEN1 (0.42) | TDP1MEN1TTRPPOXKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5205852-A | Postemergence herbicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-04-27 | — | — | US | disclosed |