Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9444495 | 0.89 | KCNH2 (0.58) | KMT2AALDH1A1MEN1KDM4EPOLB | |
| Hydrochloric Acid SCHEMBL9444430 | 0.88 | KCNH2 (0.59) | KMT2AALDH1A1MEN1KDM4EPOLB | |
| SCHEMBL10645360 | 0.79 | KMT2A (0.54) | KMT2AALDH1A1MEN1KDM4EMAPT | |
| SCHEMBL9444426 | 0.79 | MAPK1 (0.58) | KDM2BKMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL9444367 | 0.77 | ABCB1 (0.61) | ALDH1A1LMNAMAPTHTT | |
| SCHEMBL10508915 | 0.77 | MAPT (0.59) | KDM2BKMT2AALDH1A1MEN1POLB | |
| SCHEMBL9175462 | 0.76 | KCNH2 (0.61) | KMT2AALDH1A1MEN1LMNAKDM4E | |
| SCHEMBL9444358 | 0.76 | KCNH2 (0.80) | KDM2BKMT2AALDH1A1MEN1LMNA | |
| Hydrochloric Acid SCHEMBL9250962 | 0.76 | POLB (0.62) | KMT2AALDH1A1MEN1LMNAKDM4E | |
| SCHEMBL9678100 | 0.76 | KCNH2 (0.48) | KMT2AALDH1A1MEN1LMNAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235752-B1 | Piperidine derivative, pharmaceutical composition containing the same and use | EISAI CO LTD (JP) | 1993-11-18 | — | — | EP | disclosed |
| US-5179095-A | Antiarrhythmia agents | EISAI CO., LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| US-5118689-A | Antiarrhythmia agents | EISAI CO., LTD. (JP) | 1992-06-02 | — | — | US | disclosed |
| US-4996215-A | Antiarrythmia agents | EISAI CO., LTD. (JP) | 1991-02-26 | — | — | US | disclosed |
| US-4876262-A | ANTIARRHYTHMIA AGENTS | EISAI CO., LTD. (JP) | 1989-10-24 | — | — | US | disclosed |
| EP-0235752-A2 | Piperidine derivative, pharmaceutical composition containing the same and use | Eisai Co., Ltd. (JP) | 1987-09-09 | — | — | EP | disclosed |