⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9445757 | 0.75 | — | — | |
| SCHEMBL1783414 | 0.75 | — | — | |
| SCHEMBL12083655 | 0.67 | L3MBTL1 (0.37) | — | |
| SCHEMBL13090887 | 0.67 | L3MBTL1 (0.37) | — | |
| SCHEMBL13965526 | 0.66 | — | — | |
| SCHEMBL716158 | 0.64 | — | — | |
| SCHEMBL10454392 | 0.63 | — | — | |
| SCHEMBL13090810 | 0.63 | — | — | |
| SCHEMBL13090833 | 0.63 | — | — | |
| SCHEMBL6593973 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5216175-A | Polyoxoheterocyclic tetracylic derivatives | SRI INTERNATIONAL (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0479970-A1 | ANTIMALARIAL ANALOGS OF ARTEMISININ | SRI INTERNATIONAL (US) | 1992-04-15 | — | — | EP | disclosed |
| WO-1991014689-A1 | ANTIMALARIAL ANALOGS OF ARTEMISININ | SRI INTERNATIONAL (US) | 1991-10-03 | — | — | WO | disclosed |