Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | WDR5 | P61964 | 2/20 | 0.41 |
| ▸ | BRS3 | P32247 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.41 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.41 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.41 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.41 |
| ▸ | ATP4A | P20648 | 2/20 | 0.41 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.41 |
| ▸ | ATP4B | P51164 | 2/20 | 0.41 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.41 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.41 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6772312 | 0.85 | KMT2A (0.45) | KMT2ACYP1A2CYP3A4WDR5BRS3 | |
| SCHEMBL3046965 | 0.85 | KMT2A (0.45) | KMT2ACYP1A2CYP3A4WDR5BRS3 | |
| SCHEMBL6772475 | 0.85 | KMT2A (0.45) | KMT2ACYP1A2CYP3A4WDR5BRS3 | |
| SCHEMBL6770854 | 0.85 | KMT2A (0.45) | KMT2ACYP1A2CYP3A4WDR5BRS3 | |
| SCHEMBL9697309 | 0.84 | BRS3 (0.40) | KMT2ACYP1A2CYP3A4WDR5BRS3 | |
| SCHEMBL12021142 | 0.84 | BRS3 (0.46) | KMT2ACYP1A2CYP3A4WDR5BRS3 | |
| SCHEMBL7846721 | 0.83 | KMT2A (0.44) | KMT2ACYP1A2CYP3A4WDR5BRS3 | |
| SCHEMBL9445982 | 0.81 | CYP2C9 (0.42) | KMT2ACYP1A2CYP3A4WDR5BRS3 | |
| SCHEMBL9269042 | 0.81 | ALDH1A1 (0.42) | KMT2ACYP1A2CYP3A4WDR5BRS3 | |
| SCHEMBL6773081 | 0.80 | KMT2A (0.43) | KMT2ACYP1A2CYP3A4WDR5BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5215974-A | Antisecretory agents for gastrointestinal disorders; water solubility, chemical stability | AKTIEBOLAGET HASSLE (SE) | 1993-06-01 | — | — | US | disclosed |
| EP-0279149-B1 | BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Aktiebolaget Hässle (SE) | 1992-12-30 | — | — | EP | disclosed |
| EP-0332647-A1 | NEW BENZIMIDAZOLE DERIVATIVES A PROCESS FOR PRODUCTION THEREOF AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Aktiebolaget Hässle (SE) | 1989-09-20 | — | — | EP | disclosed |
| EP-0279149-A2 | Benzimidazole derivatives, process for their production and a pharmaceutical composition containing the same | Aktiebolaget Hässle (SE) | 1988-08-24 | — | — | EP | disclosed |
| WO-1988003921-A1 | NEW BENZIMIDAZOLE DERIVATIVES A PROCESS FOR PRODUCTION THEREOF AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Aktiebolaget Hässle (SE) | 1988-06-02 | — | — | WO | disclosed |