Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16681891 | 0.89 | TSHR (0.57) | TSHRPPARDTDP1TP53MEN1 | |
| SCHEMBL1679770 | 0.89 | TSHR (0.57) | TSHRPPARDTDP1TP53MEN1 | |
| SCHEMBL1679837 | 0.89 | TSHR (0.57) | TSHRPPARDTDP1TP53MEN1 | |
| SCHEMBL14457806 | 0.83 | TSHR (0.43) | TSHRPPARDTDP1TP53MEN1 | |
| SCHEMBL11443334 | 0.80 | TSHR (0.48) | TSHRPPARDTDP1TP53MEN1 | |
| SCHEMBL874362 | 0.80 | TSHR (0.48) | TSHRPPARDTDP1TP53MEN1 | |
| SCHEMBL9208492 | 0.78 | TSHR (0.46) | TSHRPPARDTDP1TP53MEN1 | |
| SCHEMBL9208480 | 0.78 | TSHR (0.46) | TSHRPPARDTDP1TP53MEN1 | |
| SCHEMBL4609885 | 0.77 | TSHR (0.50) | TSHRPPARDTDP1TP53MEN1 | |
| SCHEMBL20490115 | 0.77 | TSHR (0.50) | TSHRPPARDTDP1TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179085-A | Cerebrovascular disorders | WARNER-LAMBERT COMPANY (US) | 1993-01-12 | — | — | US | disclosed |