Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11443334 | 1.00 | TSHR (0.48) | TSHRPPARDTDP1TP53MEN1 | |
| SCHEMBL16681891 | 0.85 | TSHR (0.57) | TSHRPPARDTDP1TP53MEN1 | |
| SCHEMBL1679770 | 0.85 | TSHR (0.57) | TSHRPPARDTDP1TP53MEN1 | |
| SCHEMBL1679837 | 0.85 | TSHR (0.57) | TSHRPPARDTDP1TP53MEN1 | |
| SCHEMBL9446012 | 0.80 | TSHR (0.46) | TSHRPPARDTDP1TP53MEN1 | |
| SCHEMBL20490115 | 0.79 | TSHR (0.50) | TSHRPPARDTDP1TP53MEN1 | |
| SCHEMBL11341590 | 0.79 | TSHR (0.50) | TSHRPPARDTDP1TP53MEN1 | |
| SCHEMBL4609885 | 0.79 | TSHR (0.50) | TSHRPPARDTDP1TP53MEN1 | |
| SCHEMBL14457806 | 0.77 | TSHR (0.43) | TSHRPPARDTDP1TP53MEN1 | |
| SCHEMBL12845865 | 0.76 | TSHR (0.46) | TSHRPPARDTDP1TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077781-A1 | FLAVIN DERIVATIVES | GADWOOD ROBERT (US) | 2012-03-29 | — | — | US | disclosed |
| EP-2320734-A1 | FLAVIN DERIVATIVES | BioRelix, Inc. (US) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010019208-A1 | FLAVIN DERIVATIVES | BIORELIX PHARMACEUTICALS, INC. (US) | 2010-02-18 | — | — | WO | disclosed |
| US-5595983-A | ANTAGONIST ACTION AT AMINO ACID RECEPTORS, ANTICONVULSANTS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1997-01-21 | — | — | US | disclosed |
| US-5399693-A | Substituted piperazine-2-carboxylic acids and derivatives thereof | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1995-03-21 | — | — | US | disclosed |
| EP-0159889-B1 | 4-SUBSTITUTED PIPERAZINE-2-CARBOXYLIC ACIDS PROCESS AND PHARMACEUTICAL COMPOSITIONS | BTG INTERNATIONAL LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |
| EP-0159889-A2 | 4-Substituted piperazine-2-carboxylic acids process and pharmaceutical compositions | BTG INTERNATIONAL LIMITED (GB) | 1985-10-30 | — | — | EP | disclosed |
| US-4206156-A | ANTIMICROBIAL | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1980-06-03 | — | — | US | disclosed |
| US-4182758-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077781-A1 | FLAVIN DERIVATIVES | BLVRB, FLAD1, FDPS | TSHR 2380/4885PPARD 893/4885TDP1 763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.