Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446262 | 1.00 | P2RX4 (0.43) | P2RX4MAPTMEN1KMT2AGAA | |
| SCHEMBL9446266 | 1.00 | P2RX4 (0.43) | P2RX4MAPTMEN1KMT2AGAA | |
| SCHEMBL21439491 | 0.96 | MAPT (0.42) | P2RX4MAPTMEN1KMT2AGAA | |
| SCHEMBL31385718 | 0.91 | MAPT (0.39) | P2RX4MAPTMEN1KMT2AGAA | |
| SCHEMBL9096102 | 0.82 | ASH1L (0.36) | P2RX4MAPTMEN1KMT2APOLB | |
| SCHEMBL6536929 | 0.72 | HPGD (0.51) | MAPTMEN1KMT2AGAAAKR1C1 | |
| SCHEMBL6236285 | 0.71 | AKR1C1 (0.44) | MAPTMEN1KMT2APOLBKDM4E | |
| SCHEMBL23031679 | 0.70 | POLB (0.39) | P2RX4MAPTMEN1KMT2APOLB | |
| SCHEMBL5776078 | 0.69 | HPGD (0.60) | MAPTMEN1KMT2AGAAAKR1C1 | |
| SCHEMBL5776074 | 0.69 | HPGD (0.60) | MAPTMEN1KMT2AGAAAKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196606-A | Aromatic tertiary amines, enamines, deoxybenzoins and benzils | HAY ALLAN S (CA) | 1993-03-23 | — | — | US | disclosed |
| US-5117062-A | Aromatic tertiary amines, enamines, deoxybenzoins and benzils | HAY ALLAN S (CA) | 1992-05-26 | — | — | US | disclosed |
| US-5011998-A | Aromatic tertiary amines, enamines, deoxybenzoins and benzils | HAY ALLAN S (CA) | 1991-04-30 | — | — | US | disclosed |