Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446335 | 1.00 | GAA (0.56) | GAATDP1L3MBTL1TRPV1ALDH1A1 | |
| SCHEMBL9446347 | 1.00 | GAA (0.56) | GAATDP1L3MBTL1TRPV1ALDH1A1 | |
| SCHEMBL9446311 | 1.00 | GAA (0.56) | GAATDP1L3MBTL1TRPV1ALDH1A1 | |
| SCHEMBL9446299 | 1.00 | GAA (0.56) | GAATDP1L3MBTL1TRPV1ALDH1A1 | |
| SCHEMBL9446290 | 1.00 | GAA (0.56) | GAATDP1L3MBTL1TRPV1ALDH1A1 | |
| SCHEMBL9446300 | 1.00 | GAA (0.56) | GAATDP1L3MBTL1TRPV1ALDH1A1 | |
| SCHEMBL9446296 | 1.00 | GAA (0.56) | GAATDP1L3MBTL1TRPV1ALDH1A1 | |
| SCHEMBL9446350 | 0.93 | CNR1 (0.55) | GAATDP1L3MBTL1TRPV1ALDH1A1 | |
| SCHEMBL9446369 | 0.81 | SOAT1 (0.53) | GAATDP1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL9446297 | 0.81 | SOAT1 (0.53) | GAATDP1L3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254590-A | Enzyme inhibitors, anticholesterol, treatment of atheroscherosis, dylipidemias | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |
| EP-0508842-A1 | Aminoacylphenol derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-10-14 | — | — | EP | disclosed |