Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.52 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.52 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.52 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.52 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.52 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.52 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.52 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.52 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.52 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.52 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.52 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.52 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446335 | 0.93 | GAA (0.56) | HPGDALDH1A1TRPV1CYP1A2CYP3A4 | |
| SCHEMBL9446300 | 0.93 | GAA (0.56) | HPGDALDH1A1TRPV1CYP1A2CYP3A4 | |
| SCHEMBL9446347 | 0.93 | GAA (0.56) | HPGDALDH1A1TRPV1CYP1A2CYP3A4 | |
| SCHEMBL9446299 | 0.93 | GAA (0.56) | HPGDALDH1A1TRPV1CYP1A2CYP3A4 | |
| SCHEMBL9446306 | 0.93 | GAA (0.56) | HPGDALDH1A1TRPV1CYP1A2CYP3A4 | |
| SCHEMBL9446296 | 0.93 | GAA (0.56) | HPGDALDH1A1TRPV1CYP1A2CYP3A4 | |
| SCHEMBL9446311 | 0.93 | GAA (0.56) | HPGDALDH1A1TRPV1CYP1A2CYP3A4 | |
| SCHEMBL9446290 | 0.93 | GAA (0.56) | HPGDALDH1A1TRPV1CYP1A2CYP3A4 | |
| SCHEMBL9446316 | 0.83 | HPGD (0.59) | CNR1MAPTHPGDALDH1A1GLA | |
| SCHEMBL9446321 | 0.81 | ALDH1A1 (0.63) | CNR1MAPTHPGDALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254590-A | Enzyme inhibitors, anticholesterol, treatment of atheroscherosis, dylipidemias | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |
| EP-0508842-A1 | Aminoacylphenol derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-10-14 | — | — | EP | disclosed |