Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446328 | 1.00 | TRPV1 (0.47) | TRPV1GAATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9446348 | 1.00 | TRPV1 (0.47) | TRPV1GAATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9446352 | 1.00 | TRPV1 (0.47) | TRPV1GAATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9446309 | 1.00 | TRPV1 (0.47) | TRPV1GAATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9446336 | 1.00 | TRPV1 (0.47) | TRPV1GAATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9446325 | 1.00 | TRPV1 (0.47) | TRPV1GAATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9446301 | 0.92 | CNR1 (0.55) | TRPV1ALDH1A1HPGDCNR1CYP1A2 | |
| SCHEMBL9446323 | 0.83 | HPGD (0.48) | TRPV1GAATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9446381 | 0.83 | HPGD (0.48) | TRPV1GAATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL9446274 | 0.83 | HPGD (0.48) | TRPV1GAATDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254590-A | Enzyme inhibitors, anticholesterol, treatment of atheroscherosis, dylipidemias | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |
| EP-0508842-A1 | Aminoacylphenol derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-10-14 | — | — | EP | disclosed |