Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.55 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.52 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.52 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.52 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.52 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.52 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.52 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.52 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.52 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.52 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.52 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.52 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.52 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.52 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.52 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.52 |
| ▸ | PSMA6 | P60900 | 1/20 | 0.52 |
| ▸ | PSMA8 | Q8TAA3 | 1/20 | 0.52 |
| ▸ | PSMB7 | Q99436 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446352 | 0.92 | TRPV1 (0.47) | CNR1TRPV1HPGDCYP1A2CYP3A4 | |
| SCHEMBL9446330 | 0.92 | TRPV1 (0.47) | CNR1TRPV1HPGDCYP1A2CYP3A4 | |
| SCHEMBL9446325 | 0.92 | TRPV1 (0.47) | CNR1TRPV1HPGDCYP1A2CYP3A4 | |
| SCHEMBL9446309 | 0.92 | TRPV1 (0.47) | CNR1TRPV1HPGDCYP1A2CYP3A4 | |
| SCHEMBL9446336 | 0.92 | TRPV1 (0.47) | CNR1TRPV1HPGDCYP1A2CYP3A4 | |
| SCHEMBL9446348 | 0.92 | TRPV1 (0.47) | CNR1TRPV1HPGDCYP1A2CYP3A4 | |
| SCHEMBL9446328 | 0.92 | TRPV1 (0.47) | CNR1TRPV1HPGDCYP1A2CYP3A4 | |
| SCHEMBL9446354 | 0.86 | PSMB11 (0.58) | CNR1PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL9446317 | 0.82 | PSMB11 (0.57) | CNR1PSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL9446350 | 0.80 | CNR1 (0.55) | CNR1PSMB11PSMA7PSMB1PSMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254590-A | Enzyme inhibitors, anticholesterol, treatment of atheroscherosis, dylipidemias | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |
| EP-0508842-A1 | Aminoacylphenol derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-10-14 | — | — | EP | disclosed |