Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 3/20 | 0.53 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.53 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CETP | P11597 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446388 | 1.00 | SOAT1 (0.53) | SOAT1SOAT2ACAT1GAATDP1 | |
| SCHEMBL9446353 | 1.00 | SOAT1 (0.53) | SOAT1SOAT2ACAT1GAATDP1 | |
| SCHEMBL9446351 | 1.00 | SOAT1 (0.53) | SOAT1SOAT2ACAT1GAATDP1 | |
| SCHEMBL9446297 | 1.00 | SOAT1 (0.53) | SOAT1SOAT2ACAT1GAATDP1 | |
| SCHEMBL9446369 | 1.00 | SOAT1 (0.53) | SOAT1SOAT2ACAT1GAATDP1 | |
| SCHEMBL9446291 | 1.00 | SOAT1 (0.53) | SOAT1SOAT2ACAT1GAATDP1 | |
| SCHEMBL9446324 | 1.00 | SOAT1 (0.53) | SOAT1SOAT2ACAT1GAATDP1 | |
| SCHEMBL9446316 | 0.92 | HPGD (0.59) | SOAT1SOAT2ACAT1GAAALDH1A1 | |
| SCHEMBL9446321 | 0.90 | ALDH1A1 (0.63) | SOAT1SOAT2GAATDP1ALDH1A1 | |
| SCHEMBL9446329 | 0.88 | ALDH1A1 (0.64) | SOAT1SOAT2GAAALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5254590-A | Enzyme inhibitors, anticholesterol, treatment of atheroscherosis, dylipidemias | ADIR ET COMPAGNIE (FR) | 1993-10-19 | — | — | US | disclosed |
| EP-0508842-A1 | Aminoacylphenol derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-10-14 | — | — | EP | disclosed |