Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16545856 | 0.80 | NAAA (0.56) | TSHRHPGDNAAAHCAR2EPHX1 | |
| SCHEMBL5136187 | 0.78 | NAAA (0.52) | TSHRHPGDCA12CA1CA2 | |
| SCHEMBL1603365 | 0.78 | TSHR (0.52) | TSHRHPGDCA12CA1CA2 | |
| SCHEMBL13786723 | 0.76 | NAAA (0.52) | TSHRHPGDNAAAHCAR2EPHX1 | |
| SCHEMBL30452273 | 0.76 | NAAA (0.52) | TSHRHPGDNAAAHCAR2EPHX1 | |
| SCHEMBL28593490 | 0.76 | NAAA (0.52) | TSHRHPGDNAAAHCAR2EPHX1 | |
| SCHEMBL18864334 | 0.76 | NAAA (0.52) | TSHRHPGDNAAAHCAR2EPHX1 | |
| SCHEMBL3666982 | 0.76 | NAAA (0.52) | TSHRHPGDNAAAHCAR2EPHX1 | |
| SCHEMBL10519867 | 0.76 | NAAA (0.52) | TSHRHPGDNAAAHCAR2EPHX1 | |
| SCHEMBL30034385 | 0.76 | NAAA (0.52) | TSHRHPGDNAAAHCAR2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514482-A4 | VINYL ETHER COMPOUNDS | — | 1993-04-21 | — | — | EP | disclosed |
| EP-0514482-A1 | VINYL ETHER COMPOUNDS | ISP INVESTMENTS INC. (US) | 1992-11-25 | — | — | EP | disclosed |
| US-5147727-A | Aryloxy polyvinyl ethers | ISP INVESTMENTS INC. (US) | 1992-09-15 | — | — | US | disclosed |
| US-5147727-A | Aryloxy polyvinyl ethers | ISP INVESTMENTS INC. (US) | 1992-09-15 | — | — | US | disclosed |
| US-5082874-A | Aryloxy polyvinyl ethers | ISP INVESTMENTS INC. (US) | 1992-01-21 | — | — | US | disclosed |
| US-5082874-A | Aryloxy polyvinyl ethers | ISP INVESTMENTS INC. (US) | 1992-01-21 | — | — | US | disclosed |
| WO-1991013052-A1 | VINYL ETHER COMPOUNDS | ISP INVESTMENTS INC. (US) | 1991-09-05 | — | — | WO | disclosed |