Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 7/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446396 | 0.80 | MEN1 (0.49) | LPAR3LPAR1LPAR2 | |
| SCHEMBL27788146 | 0.77 | SMPD1 (0.53) | SMPD1LPAR3LPAR1LPAR2S1PR2 | |
| SCHEMBL10591105 | 0.77 | SMPD1 (0.53) | SMPD1LPAR3LPAR1LPAR2S1PR2 | |
| SCHEMBL2048392 | 0.75 | LPAR3 (0.55) | SMPD1LPAR3LPAR1LPAR2LPAR5 | |
| SCHEMBL18139522 | 0.75 | LPAR3 (0.55) | SMPD1LPAR3LPAR1LPAR2LPAR5 | |
| SCHEMBL18141043 | 0.75 | LPAR3 (0.55) | SMPD1LPAR3LPAR1LPAR2LPAR5 | |
| SCHEMBL4242513 | 0.75 | LPAR3 (0.55) | SMPD1LPAR3LPAR1LPAR2LPAR5 | |
| SCHEMBL18141137 | 0.75 | LPAR3 (0.55) | SMPD1LPAR3LPAR1LPAR2LPAR5 | |
| SCHEMBL18141079 | 0.75 | LPAR3 (0.55) | SMPD1LPAR3LPAR1LPAR2LPAR5 | |
| SCHEMBL18139846 | 0.75 | LPAR3 (0.55) | SMPD1LPAR3LPAR1LPAR2LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533825-A4 | ETHER LIPID-NUCLEOSIDE COVALENT CONJUGATES | — | 1993-06-02 | — | — | EP | disclosed |
| EP-0533825-A1 | ETHER LIPID-NUCLEOSIDE COVALENT CONJUGATES. | UNIV WAKE FOREST (US) | 1993-03-31 | — | — | EP | disclosed |