Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.48 |
| ▸ | PLA2G4A | P47712 | 5/20 | 0.46 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.42 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.42 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446398 | 0.91 | PLA2G4A (0.50) | MEN1FAAHMAPK1KMT2ALPAR3 | |
| SCHEMBL9446399 | 0.83 | FAAH (0.54) | MEN1FAAHMAPK1KMT2ALPAR3 | |
| SCHEMBL9446403 | 0.81 | MEN1 (0.55) | MEN1FAAHMAPK1KMT2ALPAR3 | |
| SCHEMBL9446402 | 0.80 | SMPD1 (0.44) | LPAR3LPAR1LPAR2 | |
| SCHEMBL2441860 | 0.76 | FAAH (0.51) | MEN1FAAHMAPK1KMT2ALPAR3 | |
| SCHEMBL28058368 | 0.75 | MEN1 (0.53) | MEN1FAAHMAPK1KMT2ALPAR3 | |
| SCHEMBL15709298 | 0.75 | MEN1 (0.53) | MEN1FAAHMAPK1KMT2ALPAR3 | |
| SCHEMBL18139522 | 0.72 | LPAR3 (0.55) | LPAR3LPAR1LPAR2 | |
| SCHEMBL4242513 | 0.72 | LPAR3 (0.55) | LPAR3LPAR1LPAR2 | |
| SCHEMBL18141137 | 0.72 | LPAR3 (0.55) | LPAR3LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533825-A4 | ETHER LIPID-NUCLEOSIDE COVALENT CONJUGATES | — | 1993-06-02 | — | — | EP | disclosed |
| EP-0533825-A1 | ETHER LIPID-NUCLEOSIDE COVALENT CONJUGATES. | UNIV WAKE FOREST (US) | 1993-03-31 | — | — | EP | disclosed |