Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | PGR | P06401 | 4/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | DUT | P33316 | 1/20 | 0.32 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.31 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10591389 | 0.78 | HSD17B10 (0.34) | HSD17B10ALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL9015140 | 0.75 | PSD (0.33) | GABRA2GABRB2SRC | |
| SCHEMBL9015114 | 0.73 | PSD (0.35) | GABRA2GABRB2KCNMA1MEN1KMT2A | |
| SCHEMBL9446536 | 0.71 | AKR1C3 (0.34) | GABRA2GABRB2PGRHSD17B10ALDH1A1 | |
| SCHEMBL30880273 | 0.65 | GABRA2 (0.47) | GABRA2GABRB2HSD17B10ALDH1A1LMNA | |
| SCHEMBL27396018 | 0.65 | GABRA2 (0.47) | GABRA2GABRB2HSD17B10ALDH1A1LMNA | |
| SCHEMBL30880271 | 0.65 | GABRA2 (0.47) | GABRA2GABRB2HSD17B10ALDH1A1LMNA | |
| SCHEMBL8962070 | 0.64 | PTGS1 (0.40) | ALDH1A1MAPTLMNAKCNMA1MEN1 | |
| SCHEMBL27396035 | 0.64 | GFER (0.46) | GABRA2GABRB2ALDH1A1MAPTKDM4E | |
| SCHEMBL7784924 | 0.62 | MAPT (0.39) | ALDH1A1MAPTLMNANPSR1KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5233052-A | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1993-08-03 | — | — | US | disclosed |
| US-5180734-A | INSECTICIDAL AND ACARICIDAL DIARYLPYRROLECARBONITRILE AND DIARYLNITROPYRROLE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1993-01-19 | — | — | US | disclosed |