Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10663836 | 0.84 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL4414437 | 0.81 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2PDE10AGPBAR1ALOX5AP | |
| SCHEMBL9447091 | 0.80 | CYSLTR1 (0.44) | CYSLTR1CYSLTR2PDE10AGPBAR1KDM4E | |
| SCHEMBL28791816 | 0.76 | GPBAR1 (0.49) | CYSLTR1CYSLTR2PDE10AGPBAR1ALOX5AP | |
| SCHEMBL8807037 | 0.76 | MAOB (0.60) | KDM4EALDH1A1USP2GAA | |
| SCHEMBL1423592 | 0.75 | PDE10A (0.48) | CYSLTR1CYSLTR2PDE10A | |
| SCHEMBL13626794 | 0.74 | GPBAR1 (0.47) | CYSLTR1GPBAR1ALOX5AP | |
| SCHEMBL1694951 | 0.74 | CYSLTR1 (0.76) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL9363352 | 0.74 | CYSLTR1 (0.61) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL8179931 | 0.74 | PDE10A (0.64) | CYSLTR1CYSLTR2PDE10AGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202336-A | Lipoxygenase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-13 | — | — | US | disclosed |
| US-5093340-A | Lipoxygenase enzyme inhibitors, antithrombolytic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | disclosed |
| US-5070096-A | ANTICOAGULANTS, LIPOXYGENASE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |
| EP-0261539-B1 | SUBSTITUTED PHENYL-SULPHON AMIDES | BAYER AG (DE) | 1991-03-06 | — | — | EP | disclosed |
| EP-0261539-A2 | Substituted phenyl-sulphon amides | BAYER AG (DE) | 1988-03-30 | — | — | EP | disclosed |