Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL329889 | 0.89 | TSHR (0.56) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| Isobutanol SCHEMBL5402392 | 0.87 | TSHR (0.74) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| Alcohol SCHEMBL247964 | 0.84 | TSHR (0.78) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| Ethylene Glycol SCHEMBL1401169 | 0.84 | TSHR (0.78) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| Isopropyl Alcohol SCHEMBL63840 | 0.84 | TSHR (0.88) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL21064874 | 0.84 | TSHR (1.00) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL19193 | 0.84 | — | — | |
| Propylene Glycol SCHEMBL3314707 | 0.83 | TSHR (0.50) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| Alcohol SCHEMBL23702395 | 0.82 | TSHR (0.74) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| Alcohol SCHEMBL27846676 | 0.82 | TSHR (0.74) | TSHRTDP1CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200182854-A1 | RESIN COMPOSITION AND RELIABILITY EVALUATION METHOD THEREOF AND COLOR CONVERSION FILM COMPRISING THE SAME | LG CHEM, LTD. (KR) | 2020-06-11 | — | — | US | claimed |
| CN-101231469-A | Cleaning film cleaning sheet for immersion lithography system, components, use and application thereof | UMC CORP (CN) | 2008-07-30 | — | — | CN | claimed |
| US-20080163892-A1 | CLEANING WAFER INCLUDING DETERGENT LAYER FOR EXPOSURE APPARATUS OF IMMERSION LITHOGRAPHY SYSTEM, COMPOSITION OF DETERGENT LAYER, METHOD OF USING CLEANING WAFER AND APPLICATION SYSTEM | UNITED MICROELECTRONICS CORP. (TW) | 2008-07-10 | — | — | US | claimed |
| CN-100350579-C | B-stageable underfill encapsulant and method for its application | NAT STARCH CHEM INVEST (US) | 2007-11-21 | — | — | CN | claimed |
| US-7205096-B2 | Method for forming metal pattern by using metal nanocrystals | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2007-04-17 | — | — | US | claimed |
| US-20060110686-A1 | Method for forming metal pattern by using metal nanocrystals | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2006-05-25 | — | — | US | claimed |
| CN-1639852-A | B-stageable underfill encapsulant and method for its application | NAT STARCH CHEM INVEST (US) | 2005-07-13 | — | — | CN | claimed |
| US-6558868-B2 | Method of fabricating a high aspect ratio microstructure | BROOKHAVEN SCIENCE ASSOCIATES, LLC | 2003-05-06 | — | — | US | claimed |
| US-20020146350-A1 | Real time monitoring system | LO, JIUNN-GUANG (TW) | 2002-10-10 | — | — | US | claimed |
| US-20020115016-A1 | Method of fabricating a high aspect ratio microstructure | ENERGY, UNITED STATES DEPARTMENT OF | 2002-08-22 | — | — | US | claimed |
| US-12593571-B2 | Method for preparing pixel define layer | DUK SAN NEOLUX CO., LTD. (KR) | 2026-03-31 | — | — | US | disclosed |
| US-20250383602-A1 | METHOD FOR PREPARING PIXEL DEFINE LAYER | DUK SAN NEOLUX CO., LTD. (KR) | 2025-12-18 | — | — | US | disclosed |
| US-20250374770-A1 | METHOD FOR PREPARING PIXEL DEFINE LAYER | DUK SAN NEOLUX CO., LTD. (KR) | 2025-12-04 | — | — | US | disclosed |
| US-20250362593-A1 | METHOD FOR PREPARING PIXEL DEFINE LAYER | DUK SAN NEOLUX CO., LTD. (KR) | 2025-11-27 | — | — | US | disclosed |
| US-20250318361-A1 | METHOD FOR PREPARING PIXEL DEFINE LAYER | DUK SAN NEOLUX CO., LTD. (KR) | 2025-10-09 | — | — | US | disclosed |
| US-5629136-A | POLYSILOXANES | FUJI PHOTO FILM CO., LTD. (JP) | 1997-05-13 | — | — | US | disclosed |
| US-5571658-A | PHOTOPOLYMERIZABLE PHOTOSENSITIVE LAYER AND SILICONE RUBBER LAYER WITH DIAMINE INITIATORS HAVING TERMINAL ACRYLATE GROUPS | FUJI PHOTO FILM CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0701170-A2 | Photosensitive lithographic printing plate requiring no fountain solution and process for producing the same | FUJI PHOTO FILM CO., LTD. (JP) | 1996-03-13 | — | — | EP | disclosed |
| EP-0560347-A1 | Method for preparing dry lithographic plates | Fuji Photo Film Co., Ltd. (JP) | 1993-09-15 | — | — | EP | disclosed |
| EP-0490368-A1 | PS plate requiring no dampening water | Fuji Photo Film Co., Ltd. (JP) | 1992-06-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12593571-B2 | Method for preparing pixel define layer | MEF2D, ITGB1, GRIN2D | TSHR 3115/4885TDP1 4146/4885CHRM2 368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.