Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL944726 | 0.89 | TSHR (0.70) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| Ether SCHEMBL2146705 | 0.89 | TSHR (0.70) | TSHRTDP1ALDH1A1CHRM2CHRM4 | |
| Ether SCHEMBL330790 | 0.88 | TSHR (0.61) | TSHRTDP1ALDH1A1CHRM2CHRM4 | |
| Propylene Glycol SCHEMBL701829 | 0.85 | TSHR (0.41) | TSHRTDP1ALDH1A1CHRM2CHRM4 | |
| Propylene Glycol SCHEMBL140963 | 0.83 | ALDH1A1 (0.43) | TSHRTDP1ALDH1A1LMNAHSD17B10 | |
| Propylene Glycol SCHEMBL186272 | 0.83 | ALDH1A1 (0.43) | TSHRTDP1ALDH1A1LMNAHSD17B10 | |
| Propylene Glycol SCHEMBL151562 | 0.83 | TDP1 (0.48) | TSHRTDP1ALDH1A1LMNAHSD17B10 | |
| Propylene Glycol SCHEMBL28710964 | 0.83 | TDP1 (0.48) | TSHRTDP1ALDH1A1LMNAHSD17B10 | |
| Di(Hydroxyethyl)Ether SCHEMBL597204 | 0.82 | TSHR (0.54) | TSHRALDH1A1CHRM2CHRM4CHRM1 | |
| Ethyl Acetate SCHEMBL65476 | 0.82 | ALDH1A1 (0.58) | TSHRTDP1ALDH1A1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 282 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110874025-B | Diluent composition, substrate processing method and semiconductor element manufacturing method | 易案爱富科技有限公司 | 2024-05-24 | — | — | CN | claimed |
| US-11220659-B2 | Thinner composition | ENF TECHNOLOGY CO., LTD. (KR) | 2022-01-11 | — | — | US | claimed |
| CN-110874025-A | Thinner composition, substrate processing method and semiconductor device manufacturing method | 易案爱富科技有限公司 | 2020-03-10 | — | — | CN | claimed |
| US-20200071640-A1 | THINNER COMPOSITION | ENF TECHNOLOGY CO., LTD. (KR) | 2020-03-05 | — | — | US | claimed |
| EP-2404940-B1 | Method for producing polymer composition and polymer composition | INCTEC INC (JP) | 2014-12-24 | — | — | EP | claimed |
| EP-2404940-A1 | Method for producing polymer composition and polymer composition | The Inctec Inc. (JP) | 2012-01-11 | — | — | EP | claimed |
| US-20070193960-A1 | Process for recovering organic compounds from aqueous streams containing same | DOW GLOBAL TECHNOLOGIES INC. | 2007-08-23 | — | — | US | claimed |
| EP-1720814-A2 | PROCESS FOR RECOVERING ORGANIC COMPOUNDS FROM AQUEOUS STREAMS CONTAINING SAME | The Dow Global Technologies Inc. (US) | 2006-11-15 | — | — | EP | claimed |
| WO-2005087692-A2 | PROCESS FOR RECOVERING ORGANIC COMPOUNDS FROM AQUEOUS STREAMS CONTAINING SAME | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-09-22 | — | — | WO | claimed |
| US-20250090668-A1 | GLYCOL COMPOSITIONS INCLUDING TOCOPHEROLS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2025-03-20 | — | — | US | disclosed |
| US-20240409714-A1 | GLYCOL COMPOSITIONS COMPRISING CHELANTS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-12-12 | — | — | US | disclosed |
| EP-4430152-A1 | GLYCOL COMPOSITIONS COMPRISING CHELANTS | Dow Global Technologies LLC (US) | 2024-09-18 | — | — | EP | disclosed |
| CN-118510877-A | Cleaning composition for pretreatment of metal substrates, method for the production thereof and use thereof | 巴斯夫涂料有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-118382663-A | Glycol composition comprising tocopherol | 陶氏环球技术有限责任公司 | 2024-07-23 | — | — | CN | disclosed |
| US-5380612-A | Forming electrophotographic latent image on photoconductive layer of photosensitive planographic plate, developing to form toner image, uniformly exposing photoconductor to actinic light, removing photoconductive layer with no toner image | KONICA CORPORATION (JP) | 1995-01-10 | — | — | US | disclosed |
| US-5266443-A | Presensitized plates for lithography not requiring dampening with water | FUJI PHOTO FILM CO., LTD. (JP) | 1993-11-30 | — | — | US | disclosed |
| EP-0510646-A1 | Presensitized plates for use in making lithographic printing plates not requiring dampening with water | FUJI PHOTO FILM CO., LTD. (JP) | 1992-10-28 | — | — | EP | disclosed |
| EP-0500951-A1 | HALOGEN-FREE DETERGENT COMPOSITION | NEW JAPAN CHEMICAL CO.,LTD. (JP) | 1992-09-02 | — | — | EP | disclosed |
| EP-0466070-A2 | Presensitized plates for use in making lithographic printing plates not requiring dampening with water | Fuji Photo Film Co., Ltd. (JP) | 1992-01-15 | — | — | EP | disclosed |
| US-4186122-A | POLYESTER-AMIDE-IMIDE COPOLYMERS | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1980-01-29 | — | — | US | disclosed |