Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | SDHA | P31040 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CALML3 | P27482 | 1/20 | 0.57 |
| ▸ | F10 | P00742 | 5/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pnu-82965 SCHEMBL9447627 | 1.00 | MAOA (0.59) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL9447577 | 0.94 | MAOA (0.57) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL9447588 | 0.94 | MAOA (0.57) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6191933 | 0.94 | MAOA (0.57) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6194275 | 0.94 | MAOA (0.57) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6238447 | 0.88 | MAOA (0.58) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6236130 | 0.88 | MAOA (0.58) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6236134 | 0.88 | MAOA (0.58) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6238455 | 0.88 | MAOA (0.58) | MAOAMAOBPTGS1SDHALMNA | |
| SCHEMBL6235269 | 0.87 | MAOA (0.64) | MAOAMAOBPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0311090-A1 | Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1989-04-12 | — | — | EP | claimed |
| US-4801600-A | Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-01-31 | — | — | US | claimed |
| US-5225565-A | Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones | THE UPJOHN COMPANY (US) | 1993-07-06 | — | — | US | disclosed |
| US-5182403-A | Bactericides, treatment of AIDS | THE UPJOHN COMPANY (US) | 1993-01-26 | — | — | US | disclosed |
| US-5164510-A | Bactericides | THE UPJOHN COMPANY (US) | 1992-11-17 | — | — | US | disclosed |
| US-5039690-A | Aminomethyl oxooxazolidinyl oxa or thia cycloalkylbenzene derivatives useful as antibacterial agents | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-08-13 | — | — | US | disclosed |
| US-5036093-A | Effective against grampositive bacteria including some antibiotic resistant strains | DU PONT MERCK PHARMACEUTICAL (US) | 1991-07-30 | — | — | US | disclosed |
| US-5036092-A | Effective against antibiotic resistant streptococci and staphylococci | DU PONT MERCK PHARMACEUTICAL (US) | 1991-07-30 | — | — | US | disclosed |
| US-5032605-A | Aminomethyl oxooxazolidinyl oxa or thia cycloalkylbenzene derivatives useful as antibacterial agents | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-07-16 | — | — | US | disclosed |
| EP-0434714-A1 | IN POSITION 3 SUBSTITUTED-5-BETA-AMIDOMETHYL-OXAZOLIDIN-2-ONES | THE UPJOHN COMPANY (US) | 1991-07-03 | — | — | EP | disclosed |
| US-4985429-A | Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| US-4965268-A | ADMINISTERING TO A BACTERIAL INFECTION IN A MAMMAL | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4921869-A | Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-05-01 | — | — | US | disclosed |
| US-4921869-A | Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-05-01 | — | — | US | disclosed |
| WO-1990002744-A1 | IN POSITION 3 SUBSTITUTED-5-BETA-AMIDOMETHYL-OXAZOLIDIN-2-ONES | THE UPJOHN COMPANY (US) | 1990-03-22 | — | — | WO | disclosed |
| EP-0359418-A1 | 5'-Indolinyl-5beta-amidomethyloxazolidin-2-ones, 3-(fused-ring substituted)phenyl-5beta-amidomethyloxazolidin-2-ones and 3-(nitrogen substituted)phenyl-5beta-amidomethyloxazolidin-2-ones | THE UPJOHN COMPANY (US) | 1990-03-21 | — | — | EP | disclosed |
| EP-0311090-A1 | Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1989-04-12 | — | — | EP | disclosed |
| EP-0311090-A1 | Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1989-04-12 | — | — | EP | disclosed |
| US-4801600-A | Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-01-31 | — | — | US | disclosed |
| US-4801600-A | Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-01-31 | — | — | US | disclosed |