SCHEMBL9447649

SCHEMBL9447649

CC(=O)NCC1CN(c2ccc3c(c2)CCCC3)C(=O)O1

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.59
MAOB P27338 2/20 0.59
PTGS1 P23219 2/20 0.59
SDHA P31040 2/20 0.59
LMNA P02545 1/20 0.59
CALML3 P27482 1/20 0.59
F10 P00742 7/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9447634 1.00 MAOA (0.59) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6194933 0.99 MAOA (0.58) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6194267 0.99 MAOA (0.58) MAOAMAOBPTGS1SDHALMNA
SCHEMBL9447626 0.98 MAOA (0.59) MAOAMAOBPTGS1SDHALMNA
SCHEMBL9447667 0.98 MAOA (0.59) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6195560 0.92 MAOA (0.58) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6195568 0.92 MAOA (0.58) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6210952 0.91 MAOA (0.60) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6210958 0.91 MAOA (0.60) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6195545 0.91 MAOA (0.66) MAOAMAOBPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5225565-A Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones THE UPJOHN COMPANY (US) 1993-07-06 US disclosed
US-5182403-A Bactericides, treatment of AIDS THE UPJOHN COMPANY (US) 1993-01-26 US disclosed
US-5164510-A Bactericides THE UPJOHN COMPANY (US) 1992-11-17 US disclosed
EP-0434714-A1 IN POSITION 3 SUBSTITUTED-5-BETA-AMIDOMETHYL-OXAZOLIDIN-2-ONES THE UPJOHN COMPANY (US) 1991-07-03 EP disclosed
WO-1990002744-A1 IN POSITION 3 SUBSTITUTED-5-BETA-AMIDOMETHYL-OXAZOLIDIN-2-ONES THE UPJOHN COMPANY (US) 1990-03-22 WO disclosed
EP-0359418-A1 5'-Indolinyl-5beta-amidomethyloxazolidin-2-ones, 3-(fused-ring substituted)phenyl-5beta-amidomethyloxazolidin-2-ones and 3-(nitrogen substituted)phenyl-5beta-amidomethyloxazolidin-2-ones THE UPJOHN COMPANY (US) 1990-03-21 EP disclosed