Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9448236 | 0.93 | SRD5A1 (0.42) | SRD5A1HTR2CLMNAHSD17B1MAPT | |
| SCHEMBL9447900 | 0.85 | HTR2C (0.50) | SRD5A1HTR2CLMNAHSD17B1MAPT | |
| SCHEMBL9447903 | 0.85 | HTR2C (0.50) | SRD5A1HTR2CLMNAHSD17B1MAPT | |
| SCHEMBL9448205 | 0.79 | SRD5A1 (0.45) | SRD5A1HTR2CLMNAHSD17B1MAPT | |
| Hydrochloric Acid SCHEMBL10835629 | 0.77 | HTR2C (0.52) | SRD5A1HTR2CLMNAHSD17B1MAPT | |
| SCHEMBL9448288 | 0.76 | HTR2C (0.58) | SRD5A1HTR2CLMNAHSD17B1MAPT | |
| SCHEMBL5683349 | 0.72 | SRD5A1 (0.44) | SRD5A1LMNAHSD17B1MAPTRECQL | |
| SCHEMBL5683353 | 0.72 | SRD5A1 (0.44) | SRD5A1LMNAHSD17B1MAPTRECQL | |
| SCHEMBL9448423 | 0.71 | NPY5R (0.43) | LMNAHSD17B1MAPTRECQLSMN1; SMN2 | |
| SCHEMBL12844306 | 0.71 | PPARD (0.54) | SRD5A1HTR2CCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248677-A | Nervous system disorders or antidepressants | ABBOTT LABORATORIES (US) | 1993-09-28 | — | — | US | disclosed |
| US-5180733-A | Antidepressants or nervous systen disorders | ABBOTT LABORATORIES (US) | 1993-01-19 | — | — | US | disclosed |