Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 3/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9448056 | 1.00 | STS (0.39) | STSHSD17B1SRD5A1TRPV1ADRB2 | |
| SCHEMBL9448316 | 0.92 | STS (0.39) | STSHSD17B1SRD5A1TRPV1 | |
| SCHEMBL9448311 | 0.92 | STS (0.39) | STSHSD17B1SRD5A1TRPV1 | |
| SCHEMBL9447918 | 0.84 | SLC22A1 (0.49) | SLC22A1PRCP | |
| SCHEMBL9448048 | 0.82 | NPY5R (0.48) | HSD17B1 | |
| SCHEMBL9448176 | 0.82 | SRD5A1 (0.41) | STSHSD17B1SRD5A1ADRB2 | |
| SCHEMBL9448180 | 0.82 | SRD5A1 (0.41) | STSHSD17B1SRD5A1ADRB2 | |
| SCHEMBL9448043 | 0.82 | NPY5R (0.48) | HSD17B1 | |
| Hydrochloric Acid SCHEMBL9448117 | 0.81 | SRD5A1 (0.40) | STSHSD17B1SRD5A1ADRB2 | |
| Hydrochloric Acid SCHEMBL9448267 | 0.81 | NPY5R (0.48) | HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248677-A | Nervous system disorders or antidepressants | ABBOTT LABORATORIES (US) | 1993-09-28 | — | — | US | disclosed |
| US-5180733-A | Antidepressants or nervous systen disorders | ABBOTT LABORATORIES (US) | 1993-01-19 | — | — | US | disclosed |
| EP-0461353-A1 | Biogenic amine uptake inhibitors | ABBOTT LABORATORIES (US) | 1991-12-18 | — | — | EP | disclosed |