Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 1/20 | 0.49 |
| ▸ | PRCP | P42785 | 1/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9448312 | 0.89 | PRCP (0.42) | SLC22A1PRCPCYP11B2HTR6SIGMAR1 | |
| SCHEMBL9448102 | 0.87 | PRCP (0.51) | SLC22A1PRCPCYP11B2HTR6SIGMAR1 | |
| SCHEMBL9447922 | 0.86 | STS (0.38) | SLC22A1PRCPCYP11B2SIGMAR1 | |
| SCHEMBL9448240 | 0.86 | FADS1 (0.41) | SLC22A1PRCPSIGMAR1 | |
| SCHEMBL9447915 | 0.86 | STS (0.38) | SLC22A1PRCPCYP11B2SIGMAR1 | |
| SCHEMBL9447997 | 0.86 | PRCP (0.36) | SLC22A1PRCPHTR6SIGMAR1PDPK1 | |
| SCHEMBL9448224 | 0.86 | PRCP (0.36) | SLC22A1PRCPHTR6SIGMAR1PDPK1 | |
| Hydrochloric Acid SCHEMBL9448304 | 0.85 | OPRM1 (0.36) | SLC22A1PRCPHTR6SIGMAR1PDPK1 | |
| Hydrochloric Acid SCHEMBL9448301 | 0.85 | OPRM1 (0.36) | SLC22A1PRCPHTR6SIGMAR1PDPK1 | |
| Hydrochloric Acid SCHEMBL9448069 | 0.85 | STS (0.38) | SLC22A1PRCPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248677-A | Nervous system disorders or antidepressants | ABBOTT LABORATORIES (US) | 1993-09-28 | — | — | US | disclosed |
| EP-0461353-A1 | Biogenic amine uptake inhibitors | ABBOTT LABORATORIES (US) | 1991-12-18 | — | — | EP | disclosed |