Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.37 |
| ▸ | BCHE | P06276 | 6/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.35 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.35 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 4/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9448313 | 0.89 | SSTR1 (0.35) | PTPN1PTPN2BCHESSTR1SSTR2 | |
| SCHEMBL9448369 | 0.86 | PTPN2 (0.33) | PTPN1PTPN2BCHESSTR1SSTR2 | |
| SCHEMBL9448148 | 0.78 | PTPN1 (0.36) | PTPN1PTPN2BCHESSTR1SSTR2 | |
| SCHEMBL9447950 | 0.75 | TSHR (0.39) | PTPN1CYP2D6ALDH1A1MAPK1 | |
| SCHEMBL22393136 | 0.68 | SSTR1 (0.47) | PTPN1PTPN2BCHESSTR1SSTR2 | |
| SCHEMBL15663016 | 0.68 | BCHE (0.44) | PTPN1PTPN2BCHESSTR1SSTR2 | |
| SCHEMBL9448157 | 0.68 | SSTR1 (0.48) | PTPN1PTPN2BCHESSTR1SSTR2 | |
| SCHEMBL15663017 | 0.67 | BCHE (0.43) | PTPN1PTPN2BCHESSTR1SSTR2 | |
| SCHEMBL7156237 | 0.67 | SSTR1 (0.46) | PTPN1PTPN2BCHESSTR1SSTR2 | |
| SCHEMBL7153007 | 0.67 | SSTR1 (0.46) | PTPN1PTPN2BCHESSTR1SSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532668-A1 | NOVEL -g(a)-GLUCOSIDASE INHIBITORS. | MERRELL DOW PHARMA (US) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991018915-A1 | NOVEL α-GLUCOSIDASE INHIBITORS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-12-12 | — | — | WO | disclosed |