SCHEMBL9448369

COC([C@H]1O[C@H](OC)[C@H](OCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1)[C@@H]1O[C@H](C(O)Cc2ccccc2)[C@@H](COS(=O)(=O)C(F)(F)F)[C@@](O)(Cc2ccccc2)[C@]1(O)Cc1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	PTPN2	P17706	1/20	0.33

▸	PTPN1	P18031	1/20	0.33

▸	SSTR1	P30872	1/20	0.33

▸	SSTR2	P30874	1/20	0.33

▸	SSTR4	P31391	1/20	0.33

▸	SSTR3	P32745	1/20	0.33

▸	SSTR5	P35346	1/20	0.33

▸	BCHE	P06276	4/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9448371	0.86	PTPN1 (0.37)	PTPN2PTPN1SSTR1SSTR2SSTR4
SCHEMBL9448313	0.86	SSTR1 (0.35)	PTPN2PTPN1SSTR1SSTR2SSTR4
SCHEMBL9448155	0.80	CTRB1 (0.31)	—
SCHEMBL9448114	0.79	PTPN2 (0.32)	PTPN2PTPN1BCHE
SCHEMBL7906075	0.71	SSTR1 (0.56)	PTPN2PTPN1SSTR1SSTR2SSTR4
SCHEMBL30074341	0.71	SSTR1 (0.56)	PTPN2PTPN1SSTR1SSTR2SSTR4
SCHEMBL7906072	0.71	SSTR1 (0.56)	PTPN2PTPN1SSTR1SSTR2SSTR4
SCHEMBL8992038	0.70	SSTR1 (0.54)	PTPN2PTPN1SSTR1SSTR2SSTR4
SCHEMBL8992041	0.70	SSTR1 (0.54)	PTPN2PTPN1SSTR1SSTR2SSTR4
SCHEMBL9448297	0.70	SSTR1 (0.33)	PTPN2PTPN1SSTR1SSTR2SSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0532668-A1	NOVEL -g(a)-GLUCOSIDASE INHIBITORS.	MERRELL DOW PHARMA (US)	1993-03-24	—	—	EP	disclosed
WO-1991018915-A1	NOVEL α-GLUCOSIDASE INHIBITORS	MERRELL DOW PHARMACEUTICALS INC. (US)	1991-12-12	—	—	WO	disclosed