Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1837398 | 0.80 | POLB (0.64) | POLBMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL8352708 | 0.80 | POLB (0.59) | POLBMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL4425759 | 0.79 | POLB (0.51) | POLBMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL5035396 | 0.77 | ACP3 (0.64) | ALDH1A1 | |
| SCHEMBL28888471 | 0.75 | SMN1; SMN2 (0.57) | POLBMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL14520500 | 0.75 | POLB (0.57) | POLBMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL9448871 | 0.75 | ACP3 (0.53) | LMNA | |
| SCHEMBL7261188 | 0.74 | POLB (0.65) | POLBMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL4425132 | 0.74 | HSD17B10 (0.50) | POLBMAPTLMNASMN1; SMN2 | |
| SCHEMBL4426488 | 0.74 | POLB (0.55) | POLBMAPTALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242908-A | Of dna and rna | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-07 | — | — | US | disclosed |
| EP-0440148-A1 | Use of benzylphosphonic acid derivates for the treatment of viral diseases | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-07 | — | — | EP | disclosed |