Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | GGH | Q92820 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9448871 | 0.89 | ACP3 (0.53) | ACP3CYP1A2CYP2D6 | |
| SCHEMBL11297322 | 0.81 | ACP3 (0.61) | ACP3CYP2C19SRC | |
| SCHEMBL11349187 | 0.81 | ACP3 (0.68) | ACP3ALDH1A1CYP2D6SRC | |
| SCHEMBL10928799 | 0.79 | ACP3 (0.66) | ACP3SRC | |
| SCHEMBL7746269 | 0.78 | ACP3 (0.68) | ACP3SRC | |
| SCHEMBL9448849 | 0.77 | POLB (0.58) | ALDH1A1 | |
| SCHEMBL1246417 | 0.76 | ACP3 (0.62) | ACP3SRC | |
| SCHEMBL5293935 | 0.76 | ACP3 (0.62) | ACP3SRC | |
| SCHEMBL4454292 | 0.76 | ACP3 (0.66) | ACP3SRC | |
| SCHEMBL3674189 | 0.76 | CYP2D6 (0.54) | ALDH1A1CYP1A2CYP2D6TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896392-A1 | A-[E)-2-(5,6,7,8-TETRAHYDRO-5,5,8,8-TETRAMETHYL-2-NAPTHALENYL)-1-PROPENYL]BENZOIC ACID ANALOGS AND METHOD OF MANUFACTURE AND AND USE THEREOF | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007005568-A1 | A-[(E)-2-(5,6,7,8-TETRAHYDRO-5,5,8,8-TETRAMETHYL-2-NAPTHALENYL)-1-PROPENYL]BENZOIC ACID ANALOGS AND METHOD OF MANUFACTURE AND AND USE THEREOF | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-01-11 | — | — | WO | disclosed |