Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449125 | 1.00 | DGAT1 (0.44) | DGAT1HCAR2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL14949704 | 0.87 | DGAT1 (0.39) | DGAT1HCAR2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL9342926 | 0.87 | DGAT1 (0.39) | DGAT1HCAR2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL65239 | 0.83 | — | — | |
| SCHEMBL2501541 | 0.83 | DGAT1 (0.37) | DGAT1HCAR2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL2012274 | 0.83 | DGAT1 (0.37) | DGAT1HCAR2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL11748066 | 0.81 | DGAT1 (0.35) | DGAT1ALDH1A1TSHR | |
| SCHEMBL17502419 | 0.81 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL17502421 | 0.81 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL13017864 | 0.81 | DGAT1 (0.35) | DGAT1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189198-A | PROCESS FOR PREPARING UNSATURATED DICARBOXYLIC ACID DIESTERS | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1993-02-23 | — | — | US | disclosed |
| EP-0457197-A1 | Process for preparing unsaturated dicarboxylic acid diesters | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |