Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | IDE | P14735 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9657735 | 0.91 | TSHR (0.43) | ALDH1A1TSHRGAAPOLBTHRB | |
| SCHEMBL9643286 | 0.83 | ABCB11 (0.45) | ALDH1A1TSHRGAAPOLBMEN1 | |
| SCHEMBL9642645 | 0.83 | ABCB11 (0.45) | ALDH1A1TSHRGAAPOLBMEN1 | |
| SCHEMBL9642519 | 0.82 | ABCB11 (0.59) | ALDH1A1TSHRGAAPOLBMEN1 | |
| SCHEMBL9643229 | 0.82 | ABCB11 (0.59) | ALDH1A1TSHRGAAPOLBMEN1 | |
| SCHEMBL9641846 | 0.79 | ABCB11 (0.43) | ALDH1A1TSHRGAAPOLBMEN1 | |
| SCHEMBL9642813 | 0.79 | ABCB11 (0.43) | ALDH1A1TSHRGAAPOLBMEN1 | |
| SCHEMBL9642151 | 0.79 | ABCB11 (0.43) | ALDH1A1TSHRGAAPOLBMEN1 | |
| SCHEMBL9643427 | 0.79 | ABCB11 (0.43) | ALDH1A1TSHRGAAPOLBMEN1 | |
| SCHEMBL9448818 | 0.78 | DHODH (0.40) | ALDH1A1GAAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242946-A | Treating herpes Viral infections | BIO-MEGA, INC. (CA) | 1993-09-07 | — | — | US | claimed |
| US-5242946-A | Treating herpes Viral infections | BIO-MEGA, INC. (CA) | 1993-09-07 | — | — | US | disclosed |