Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12212071 | 0.82 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1KDM4EKMT2ATDP1 | |
| SCHEMBL15367926 | 0.81 | ACP3 (0.46) | ALDH1A1L3MBTL1KDM4ETDP1POLB | |
| SCHEMBL8958927 | 0.79 | HPGD (0.43) | ALDH1A1L3MBTL1TAAR1KDM4EMAPT | |
| SCHEMBL3293885 | 0.77 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1KDM4EKMT2ATDP1 | |
| SCHEMBL916350 | 0.76 | CCNT1 (0.43) | ALDH1A1TAAR1KMT2AMAPTHPGD | |
| SCHEMBL5403459 | 0.76 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1KDM4EKMT2AHPGD | |
| SCHEMBL9448848 | 0.72 | MAPT (0.37) | ALDH1A1TAAR1KDM4EMAPTHPGD | |
| SCHEMBL916701 | 0.72 | KDM4E (0.36) | ALDH1A1KDM4EHPGDHTTMAOB | |
| SCHEMBL12212128 | 0.72 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1KMT2AMAPTPOLB | |
| SCHEMBL9449102 | 0.71 | CYP3A4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242908-A | Of dna and rna | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-07 | — | — | US | disclosed |
| CN-1053793-A | Use the disease that benzylphosphonic acid derivatives for treatment is caused by virus | HOECHST AG (DE) | 1991-08-14 | — | — | CN | disclosed |
| EP-0440148-A1 | Use of benzylphosphonic acid derivates for the treatment of viral diseases | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-07 | — | — | EP | disclosed |