Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.71 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.71 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.71 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.71 |
| ▸ | IMPDH2 | P12268 | 18/20 | 0.60 |
| ▸ | IMPDH1 | P20839 | 15/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449381 | 1.00 | ALDH1A1 (0.71) | ALDH1A1LMNAHPGDABCC4NR1I2 | |
| SCHEMBL9807970 | 0.94 | ALDH1A1 (0.81) | ALDH1A1LMNAHPGDABCC4NR1I2 | |
| SCHEMBL9807972 | 0.94 | ALDH1A1 (0.81) | ALDH1A1LMNAHPGDABCC4NR1I2 | |
| Hydrochloric Acid SCHEMBL9807986 | 0.93 | ALDH1A1 (0.80) | ALDH1A1LMNAHPGDABCC4NR1I2 | |
| Hydrochloric Acid SCHEMBL9807983 | 0.93 | ALDH1A1 (0.80) | ALDH1A1LMNAHPGDABCC4NR1I2 | |
| SCHEMBL1153725 | 0.90 | ALDH1A1 (0.68) | ALDH1A1LMNAHPGDABCC4NR1I2 | |
| SCHEMBL1153722 | 0.90 | ALDH1A1 (0.68) | ALDH1A1LMNAHPGDABCC4NR1I2 | |
| SCHEMBL1152322 | 0.89 | ALDH1A1 (0.87) | ALDH1A1LMNAHPGDABCC4NR1I2 | |
| SCHEMBL1152328 | 0.89 | ALDH1A1 (0.87) | ALDH1A1LMNAHPGDABCC4NR1I2 | |
| SCHEMBL1151899 | 0.89 | ALDH1A1 (0.81) | ALDH1A1LMNAHPGDABCC4NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5177072-A | Treatment of autoimmune inflammatory, and psoriatic diseases with heterocyclic aminoalkyl esters of mycophenolic acid and derivatives | SYNTEX (U.S.A.) INC. (US) | 1993-01-05 | — | — | US | disclosed |
| US-4861776-A | Heterocyclic aminoalkyl esters of mycophenolic acid and derivatives thereof, compositions and use | SYNTEX (U.S.A) INC. (US) | 1989-08-29 | — | — | US | disclosed |
| US-4748173-A | IMMUNOSUPRESSIVE, ANTIINFLAMMATORY, ANTITUMOR, ANTIVIRAL, AND ANTIPSORIASIS AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-05-31 | — | — | US | disclosed |
| US-4727069-A | ANTIBODY INHIBITORS, ANTIINFLAMMATORY, ANTITUMOR AGENTS, VIRICIDES, AND ANTIPSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-02-23 | — | — | US | disclosed |