Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | SELE | P16581 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.33 |
| ▸ | ATP4A | P20648 | 1/20 | 0.33 |
| ▸ | ATP4B | P51164 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.33 |
| ▸ | BRS3 | P32247 | 1/20 | 0.32 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3794302 | 0.81 | NPC1 (0.39) | AGXTNPC1RAB9AKDM4CL3MBTL1 | |
| SCHEMBL19299872 | 0.70 | KDM4C (0.35) | NPC1RAB9AKDM4CL3MBTL1ICAM1 | |
| SCHEMBL1564476 | 0.69 | NPC1 (0.39) | NPC1RAB9AKDM4CL3MBTL1ICAM1 | |
| SCHEMBL26026519 | 0.69 | AGXT (0.70) | AGXTPDE10AHSP90AA1HSP90AB1SHMT2 | |
| SCHEMBL31021642 | 0.68 | L3MBTL1 (0.43) | NPC1RAB9AKDM4CL3MBTL1ICAM1 | |
| SCHEMBL10988084 | 0.68 | NPC1 (0.36) | NPC1RAB9AKDM4CL3MBTL1ICAM1 | |
| SCHEMBL23388043 | 0.68 | NPC1 (0.42) | NPC1RAB9AKDM4CL3MBTL1ICAM1 | |
| SCHEMBL29749517 | 0.68 | NPC1 (0.42) | NPC1RAB9AKDM4CL3MBTL1ICAM1 | |
| SCHEMBL18355699 | 0.67 | TACR1 (0.46) | NPC1RAB9AKDM4CKMT2AMEN1 | |
| SCHEMBL3139208 | 0.67 | NPC1 (0.40) | NPC1RAB9AKDM4CL3MBTL1ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5070432-A | — | — | None | — | — | JP | disclosed |
| JP-H0570432-A | NOVEL 4-METHOXY-2-(2-TETRAHYDROPYRANYLOXYMETHYL) PYRIDINE COMPOUND AND ITS INTERMEDIATE AND THEIR PRODUCTION | TOKYO TANABE CO LTD | 1993-03-23 | — | — | JP | disclosed |