Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.69 |
| ▸ | EBP | Q15125 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9449875 | 0.96 | SIGMAR1 (0.63) | SIGMAR1EBPKDM4ELMNAHTT | |
| SCHEMBL9449653 | 0.92 | SIGMAR1 (0.62) | SIGMAR1EBPKDM4ELMNAHTT | |
| SCHEMBL16322104 | 0.92 | SIGMAR1 (0.62) | SIGMAR1EBPKDM4ELMNAHTT | |
| SCHEMBL10582736 | 0.90 | SIGMAR1 (0.60) | SIGMAR1EBPKDM4ELMNAHTT | |
| SCHEMBL15210850 | 0.83 | SIGMAR1 (0.55) | SIGMAR1EBPKDM4ELMNAHTT | |
| SCHEMBL9449643 | 0.83 | SIGMAR1 (0.55) | SIGMAR1EBPKDM4ELMNAHTT | |
| SCHEMBL23309796 | 0.82 | SIGMAR1 (1.00) | SIGMAR1EBPKDM4ELMNAHTT | |
| Tridemorph SCHEMBL28670 | 0.82 | SIGMAR1 (1.00) | SIGMAR1EBPKDM4ELMNAHTT | |
| SCHEMBL120500 | 0.82 | SIGMAR1 (1.00) | SIGMAR1EBPKDM4ELMNAHTT | |
| SCHEMBL22222412 | 0.82 | SIGMAR1 (1.00) | SIGMAR1EBPKDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5240925-A | FUNGICIDAL 2-ARYL-2-CYANO-2-(HETEROCYCLYLALKYL)ETHYL-1,2,4-TRIAZOLES | ROHM AND HAAS COMPANY (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0529973-A1 | Fungicidal 2-aryl-2-cyano-2-(heterocyclylalkyl)ethyl-1,2,4-triazoles | ROHM AND HAAS COMPANY (US) | 1993-03-03 | — | — | EP | disclosed |